A Sustained Reduction in Serum Cholinesterase Enzyme Activity Predicts Patient Outcome following Sepsis

Figure 2

Activity pattern of the inflammatory biomarkers in patients with sepsis. Activity of PCT (a, b), MR-proADM (c, d), IL-6 (e, f), and TNF-α (g, h) was measured at the time point of sepsis detection (0) as well as 1, 2, 7, 14, 21, and 28 days later in patients who survived (open circles) and in those who died within 90 days (closed circles). Magnified time lines (b, d, f, h) represent measurements obtained within the first two days after the sepsis detection. Dark gray-shaded areas indicate time periods with the statistical difference between the patient groups (, Mann–Whitney U test). Data points are medians. PCT: procalcitonin; MR-proADM: midrange proadrenomedullin; IL-6: interleukin 6; TNF-α: tumor necrosis factor alpha.