Plasma Energy-Balance Metabolites Discriminate Asymptomatic Patients with Peripheral Artery Disease

Table 3

Metabolite concentration in patients segregated according to the presence of diabetes.

Metabolite	Diabetes
	No	Yes
3-hydroxybutirate	0.27 (0.13–0.39)	0.27 (0.14–0.40)
Aconitate	3.75 (2.38–6.50)	4.60 (2.67–6.28)
α-Ketoglutarate	4.24 (2.56–7.22)	4.13 (2.76–6.50)
Alanine	210.6 (147.5–266.3)	189.6 (139.0–271.4)
Aspartate	172.5 (133.3–215.8)	179.7 (143.0–225.1)
(Iso)citrate	721.7 (584.42–867.3)	665.6 (538.0–880.5)
Fumarate	0.26 (0.19–0.41)	0.24 (0.18–0.37)
Glucose	4546.0 (4104.0–5115.5)	4959.3 (4040.8–5804.9)^a
Glutamate	1457.2 (743.0–2912.4)	1416.9 (671.7–2684.2)
Glutamine	5073.4 (3054.2–7754.5)	4742.5 (1842.3–8881.2)
Isoleucine	57.14 (47.71–63.99)	63.68 (52.83–75.20)^a
Lactate	367.2 (283.9–423.6)	341.0 (297.1–441.6)
Leucine	85.07 (70.62–94.86)	86.68 (69.33–109.65)
Malate	2.38 (1.85–4.31)	2.45 (1.88–3.56)
Pyruvate	12.47 (3.64–22.87)	12.83 (3.55–21.89)
Serine	147.5 (101.7–167.4)	137.6 (109.4–169.5)
Succinate	9.57 (8.35–15.11)	9.70 (8.47–15.23)
Succinyl-CoA	10.14 (7.74–15.12)	10.46 (7.37–17.62)
Valine	102.0 (83.0–129.4)	104.1 (80.7–138.9)

^a.