Huanglian-Wendan Decoction Inhibits NF-κB/NLRP3 Inflammasome Activation in Liver and Brain of Rats Exposed to Chronic Unpredictable Mild Stress

Table 5

Effects of Huanglian-Wendan decoction on sucrose solution consumption in CUMS rats.

Groups	Duration (week)
	0	2	4	6	8	10	12
Non-CUMS + vehicle	19.1 ± 0.9	20.0 ± 0.6	20.7 ± 0.8	21.1 ± 1.1	22.5 ± 0.8	22.5 ± 0.6	22.9 ± 0.5
CUMS + vehicle	19.1 ± 1.2	15.8 ± 0.8^###	16.0 ± 0.6^###	15.1 ± 0.6^###	15.4 ± 0.5^###	15.0 ± 0.7^###	15.0 ± 0.7^###
Huanglian-Wendan decoction (5690 mg/kg)	19.1 ± 0.9	14.3 ± 0.8^###	14.4 ± 0.6^###	14.7 ± 0.8^###	19.4 ± 1.1	20.2 ± 1.4	21.0 ± 1.3
Huanglian-Wendan decoction (11,380 mg/kg)	18.6 ± 0.8	15.4 ± 0.8^###	14.6 ± 0.6^###	14.5 ± 0.5^###	17.8 ± 1.2	18.6 ± 1.2	20.1 ± 1.0
Fluoxetine (10 mg/kg)	19.2 ± 0.8	14.5 ± 0.5^###	15.0 ± 0.4^###	14.7 ± 0.5^###	20.2 ± 0.3	21.6 ± 0.5	21.8 ± 0.7

All data were expressed as (). compared with the non-CUMS group; and compared with the CUMS group.