The Role of Circulating Regulatory T Cell Levels on Subclinical Atherosclerosis and Cardiovascular Risk Factors in Women with Systemic Lupus Erythematosus
Table 2
Clinical characteristics and biological parameters in patients with and without abnormal IMT.
Characteristic
Abnormal carotid IMT ()
Normal carotid IMT ()
value
Age (years), mean ± SD
0.71
Menopause, (%)
10 (25.64)
5 (18.51)
0.39
Smoking, (%)
3 (7.69)
0 (0.0)
0.23
Diabetes, (%)
0 (0)
2 (7.40)
0.14
Hypertension, (%)
8 (20.5)
2 (7.4)
0.13
BMI (kg/m2), mean ± SD
0.93
Waist circumference, mean ± SD
0.29
Systolic BP (mm Hg), mean ± SD
0.09
Diastolic BP (mm Hg), mean ± SD
0.76
Total cholesterol, mean ± SD
0.27
LDL cholesterol, mean ± SD
0.57
HDL cholesterol, mean ± SD
0.50
Triglycerides, mean ± SD
0.55
10-year risk of heart attack (%), mean ± SD
0.24
Duration of SLE disease (years), median (IQR)
10 (7. 11)
10 (7. 13)
0.98
SLEDAI-2K score, median (IQR)
1 (0. 3)
1 (1. 4)
0.50
Antiphospholipid syndrome, (%)
1 (2.6)
5 (18.5)
0.03
Prednisone daily dose, mg, mean ± SD
0.39
Cumulative dose of steroid treatment (g), median (IQR)
22.05 (9.75. 36.00)
24.95 (8.32. 37.72)
0.13
Antimalarials, (%)
29 (74.35)
20 (74.07)
0.60
Immunosuppressive drugs, (%)
24 (61.53)
15 (55.55)
0.32
Statin therapy, (%)
11 (28.20)
9 (33.33)
0.42
Antiplatelet therapy, (%)
11 (28.20)
9 (33.33)
0.36
Vitamin K antagonist therapy,
1 (2.5)
4 (14.8)
0.11
Antihypertensive therapy, (%)
10 (25.6)
7 (25.9)
0.86
BMI: body mass index; BP: blood pressure; HDL: high-density lipoprotein; LDL: low-density lipoprotein; SD: standard deviation; SLEDAI-2K: SLE Disease Activity Index 2000.
