Upregulation of Cardiac IL-10 and Downregulation of IFN-γ in Balb/c IL-4^−/− in Acute Chagasic Myocarditis due to Colombian Strain of Trypanosoma cruzi

Figure 4

Cytokine production in splenocytes of WT Balb/c and IL-4^−/− Balb/c mice infected with Colombian strain of T. cruzi stimulated with 10 μg/ml of concanavalin A in the acute phase of experimental Chagas’ disease. Fold change between nonstimulated versus CON-A stimulated splenocytes. Student’s -test. Bars represent the mean, and vertical lines represent the standard error. Significant differences between infected versus uninfected animals.