Research Article
Placental Ras Regulates Inflammation Associated with Maternal Obesity
| | Lean cohort ( patients) | Obese cohort ( patients) |
| Maternal age | 31.8 ± 1.1 | 32.27 ± 0.5 | Prepregnancy BMI (kg/m2) | 23.6 ± 0.6# | 40.2 ± 2.1∗ | Delivery BMI (kg/m2) | 29.0 ± 0.9# | 42.0 ± 1.9∗ | Fasting OGTT (mmol/l) | 4.3 ± 0.1 | 4.5 ± 0.1 | 1 h OGTT (mmol/l) | 6.1 ± 0.3 | 7.2 ± 0.3 | 2 h OGTT (mmol/l) | 5.5 ± 0.2 | 5.5 ± 0.3 | Gestational age (weeks) | 38.8 ± 0.2 | 38.8 ± 0.1 | Neonate birth weight (g) | 3406 ± 122 | 3543 ± 139 | Fetal gender | 8 male; 7 female | 5 male; 10 female | Gravida | 2.4 ± 0.2 | 2.8 ± 0.5 | Parity | 2.0 ± 0.2 | 2.5 ± 0.4 |
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Values represent mean ± SEM. OGTT: oral glucose tolerance test. vs. lean (Mann-Whitney U test). |