sST2 as a New Biomarker of Chronic Kidney Disease-Induced Cardiac Remodeling: Impact on Risk Prediction

Table 2

Univariate Cox analysis predictive of cardiovascular events and/or death composite outcome.

Variable	HR [95% CI]
Age (years)	1.052 [1.031–1.072]	<0.001
Female	0.420 [0.251–0.704]	0.001
SBP (mmHg)	0.992 [0.981–1.004]	0.209
DBP (mmHg)	0.986 [0.966–1.006]	0.167
LAVI (mL/m^2)	1.050 [1.015–1.086]	0.005
LAD (mm)	1.074 [1.030–1.119]	0.001
LVMI (g/m^2)	1.004 [0.998–1.009]	0.183
E/A	1.010 [0.607–1.681]	0.969
Log hs-cTnT (ng/L)	5.152 [2.659–9.983]	<0.001
Log NT-proBNP (ng/L)	1.650 [1.116–2.439]	0.012
Log CRP (mg/L)	2.155 [1.388–3.346]	0.001
Log sST2 (ng/mL)	2.836 [0.532–15.134]	0.222
Log PINP (ng/mL)	0.836 [0.340–2.057]	0.696
eGFR (mL/min/1.73 m^2)	0.992 [0.981–1.003]	0.172
Na (mmol/L)	0.985 [0.908–1.069]	0.720
Hb (g/dL)	0.991 [0.852–1.153]	0.909

DBP: diastolic blood pressure, eGFR: estimated glomerular filtration rate, Hb: hemoglobin, LAD: left atrial diameter, LAVI: left atrial volume index, LVMI: left ventricular mass index, SBP: systolic blood pressure.