Plasma Cytokine Levels in Fibromyalgia and Their Response to 15 Weeks of Progressive Resistance Exercise or Relaxation Therapy
Table 5
Changes in cytokine levels before and after the interventions in women with fibromyalgia.
pg/mL
Exercise
Relaxation
Before
Δ
Before
Δ
IFN-γ
11.2 (9.0)
−1.8 (9.2)
9.7 (12.3)
−0.4 (8.6)
IL-1β
0.9 (1.9)
0.0 (1.3)
0.0 (1.6)
0.6 (1.6)
IL-2
3.3 (4.9)
−0.3 (2.7)
2.8 (3.1)
−0.3 (1.6)
IL-6
1.7 (2.5)
−0.2 (1.2)
2.1 (2.4)
0.2 (1.9)
IL-8
1.6 (1.9)#
−0.3 (1.6)
0.8 (1.7)
0.0 (1.3)
IL-10
8.0 (9.7)
−1.0 (6.3)
7.9 (9.6)
0.8 (7.4)
IL-17A
10.8 (10.1)
−2.1 (7.6)
9.2 (7.5)
−0.7 (5.9)
TNF-α
4.5 (2.2)
−0.4 (1.8)
4.0 (1.7)
−0.3 (2.0)
IL-1ra
27.9 (67.8)
22.1 (60.8)
44.7 (105.4)
21.4 (91.5)
IP-10
379.7 (230.4)
2.3 (180.4)
398.5 (219.7)
−33.5 (184.3)
MCP-1
318.0 (124.5)
7.1 (131.5)
289.6 (151.0)
23.6 (76.3)
eotaxin
107.0 (42.6)
−11.4 (53.0)
106.9 (52.6)
−8.6 (34.6)
Data show median (interquartile range) cytokine levels before and their change (Δ) after 15 weeks of progressive resistance exercise or relaxation therapy. Italic font indicates significant difference between groups (Mann–Whitney U-test; ).
