Sepsis Induces a Dysregulated Neutrophil Phenotype That Is Associated with Increased Mortality

<div>The impact of acidosis on neutrophil extracellular trap formation. (a) Correlation between standardized base excess and neutrophil extracellular trap formation in 99 patients with sepsis. Spearman’s rho suggests that reduction in NET formation is associated with worsening acidosis. (b) Effect of acidosis on the NETs generated from the neutrophils of 5 healthy donors.</div>

Mediators of Inflammation

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Figure 4

Figure 4: Sepsis Induces a Dysregulated Neutrophil Phenotype That Is Associated with Increased Mortality 