Research Article
Overexpression of Tear Inflammatory Cytokines as Additional Finding in Keratoconus Patients and Their First Degree Family Members
Table 1
Tear-fluid cytokine mean concentrations measured in pg/mL in keratoconus, first degree family members, and controls.
| | Cytokines (pg/mL) | Keratoconus | First degree family members | Controls | value (test) |
| | IFN gamma | 157.75 (±69.68) | 144.59 (±63.61) | 106.07 (±19.93) | 0.0374 (ANOVA) | | IL-10 | 181.61 (±78.55) | 163.60 (70.97) | 123.56 (±30.96) | 0.0447 (ANOVA) | | IL-1 beta | 113.52 (±34.86) | 107.06 (±24.71) | 83.45 (±18.07) | 0.0091 (ANOVA) | | IL-4 | 461.67 (±283.20) | 378.37 (±242.48) | 159.21 (±99.72) | 0.0018 (ANOVA) | | IL-6 | 122.32 (±18.63) | 112.41 (±20.38) | 100.31 (±14.13) | 0.0051 (ANOVA) | | RANTES | 185.37 (±38.73) | 169.61 (±37.95) | 174.14 (±65.67) | 0.3061 (Kruskal-Wallis) | | TNF alpha | 131.80 (±34.29) | 125.33 (±28.08) | 108.07 (±15.84) | 0.05 (ANOVA) |
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