Research Article

Overexpression of CD44 Variant 9: A Novel Cancer Stem Cell Marker in Human Cholangiocarcinoma in Relation to Inflammation

Table 1

Clinicopathological information of normal subjects and CCA patients.

CharacteristicsNormal liver

No. (%)
Non-OV-CCA

No. (%)
OV-CCA

No. (%)
Statistical significance

Age (years)
 ≤4015 (71.4)12 (12.2)2 (6.1)
 >406 (28.6)86 (87.8)31 (93.9)
Sex
 Male12 (57.1)56 (57.1)26 (78.8)n.s.
 Female9 (42.9)42 (42.9)7 (21.2)
TNM classification
 Ta
  T12 (2.0)1 (3.7)##
  T251 (52.0)5 (18.5)
  T343 (43.9)9 (33.3)
  T42 (2.0)12 (44.4)
 Na
  N067 (68.4)3 (20.0)##
  N131 (31.6)12 (80.0)
 Ma
  M095 (96.9)24 (85.7)#
  M13 (3.1)4 (14.3)
Tumor stagea
 I2 (2.0)0 (0.0)##
 II40 (40.8)3 (11.5)
 III27 (27.6)7 (26.9)
 IV29 (29.6)16 (61.6)

OV: Opisthorchis viverrini; CCA: cholangiocarcinoma; n.s.: not significant. compared to that of the normal liver group. and compared to that of the non-OV-CCA group. aPatients missing clinical information are not included in the statistical analyses.