Overexpression of CD44 Variant 9: A Novel Cancer Stem Cell Marker in Human Cholangiocarcinoma in Relation to Inflammation
Table 1
Clinicopathological information of normal subjects and CCA patients.
Characteristics
Normal liver
No. (%)
Non-OV-CCA
No. (%)
OV-CCA
No. (%)
Statistical significance
Age (years)
≤40
15 (71.4)
12 (12.2)
2 (6.1)
>40
6 (28.6)
86 (87.8)
31 (93.9)
Sex
Male
12 (57.1)
56 (57.1)
26 (78.8)
n.s.
Female
9 (42.9)
42 (42.9)
7 (21.2)
TNM classification
Ta
T1
—
2 (2.0)
1 (3.7)
##
T2
—
51 (52.0)
5 (18.5)
T3
—
43 (43.9)
9 (33.3)
T4
—
2 (2.0)
12 (44.4)
Na
—
N0
—
67 (68.4)
3 (20.0)
##
N1
—
31 (31.6)
12 (80.0)
Ma
—
M0
—
95 (96.9)
24 (85.7)
#
M1
—
3 (3.1)
4 (14.3)
Tumor stagea
I
—
2 (2.0)
0 (0.0)
##
II
—
40 (40.8)
3 (11.5)
III
—
27 (27.6)
7 (26.9)
IV
—
29 (29.6)
16 (61.6)
OV: Opisthorchis viverrini; CCA: cholangiocarcinoma; n.s.: not significant. compared to that of the normal liver group. and compared to that of the non-OV-CCA group. aPatients missing clinical information are not included in the statistical analyses.