Identifying Therapeutic Targets for Sepsis Research: A Characterization Study of the Inflammatory Players in the Cecal Ligation and Puncture Model
Table 2
Cell blood count and white blood cell differentials.
Parameter
sham
CLP day 2
CLP day 7
Hemoglobin (g/dl)
12.88 ± 0.74
11.97 ± 0.64
2.81 ± 0.73
Erythrocytes (×106/μl)
8.32 ± 0.39
7.62 ± 0.42
1.78 ± 0.48
Thrombocytes (×103/μl)
1067.00 ± 64.17
517.6 ± 91.68
1894 ± 196.6
Leukocytes (×103/μl)
2.21 ± 0.12
2.30 ± 0.30
7.23 ± 1.84
Neutrophils (%)
4.20 ± 0.58
4.87 ± 0.50
2.33 ± 0.62
Lymphocytes (%)
59.12 ± 6.98
23.30 ± 3.12
22.19 ± 2.97
Monocytes (%)
30.24 ± 7.62
63.24 ± 3.42
60.79 ± 4.42
Eosinophils (%)
0.40 ± 0.11
0.22 ± 0.10
0.29 ± 0.07
Basophils (%)
1.50 ± 0.83
1.87 ± 0.86
0.44 ± 0.10
Undifferentiated/immature (%)
5.56 ± 0.91
7.56 ± 1.45
11.88 ± 1.39
Cell blood count and white blood cell differential of whole blood obtained by cardiac puncture in septic (CLP day 2 or CLP day 7) and control animals (sham); the different subsets of leukocytes are expressed as percentage of the leukocyte population. One-way ANOVA with post hoc Dunnett test or Kruskal–Wallis test with post hoc Dunn’s test as appropriate. /group. ,, and .