Research Article
Butyrylcholinesterase Levels on Admission Predict Severity and 12-Month Mortality in Hospitalized AIDS Patients
Table 2
Risk factors for mortality of patients in univariate/multivariate Cox proportional hazards models.
| | Factor | Number () | Deaths () | Univariate | Multivariate | | HR | 95% CI | | HR | 95% CI | |
| | Sex | | | | | 0.817 | | | — | | Male | 441 (87.3) | 74 (16.8) | 1.0 | 0.9–1.1 | | | | Female | 64 (12.7) | 10 (15.6) | 1 | | | | | Age (years) | | | | | 0.020 | | | — | | <30 | 123 (24.4) | 12 (9.8) | 1 | | | | | ≥30 | 382 (75.6) | 72 (18.8) | 2.1 | 1.1–3.8 | | | | BMI (kg/m2) | | | | | | | | | | Missing data | 37 (7.3) | 22 (59.5) | | | | | | | | <18 | 110 (21.8) | 21 (19.1) | 1.8 | 1.0–3.0 | 0.036 | | | — | | ≥18 | 358 (70.9) | 41 (11.5) | 1 | | | | | | | WHO stage | | | | | <0.001 | | | 0.008 | | I/II/III | 217 (43.0) | 19 (8.8) | 1.0 | | 1.0 | | | IV | 288 (57.0) | 65 (22.6) | 5.6 | 3.0–10.5 | 2.9 | 1.3–6.5 | | CD4 count (cells/μL) | | | | | <0.001 | | | 0.007 | | Missing data | 71 (14.1) | 15 (21.1) | | | | | | <50 | 181 (35.8) | 45 (24.9) | 3.0 | 1.8–4.9 | 2.4 | 1.3-4.4 | | ≥50 | 253 (50.1) | 24 (9.5) | 1 | | 1 | | | Serum sodium (mmol/L) | | | | | 0.002 | | | — | | Missing data | 42 (8.3) | 5 (11.9) | | | | | | <130 | 28 (5.5) | 10 (35.7) | 1 | | | | | ≥130 | 435 (86.1) | 69 (15.9) | 2.9 | 1.5–5.6 | | | | Hemoglobin (g/L) | | | | | 0.035 | | | — | | Missing data | 33 (6.5) | 4 (12.1) | | | | | | <110 | 166 (32.9) | 37 (22.3) | 1.6 | 1.0–2.5 | | | | ≥110 | 306 (60.6) | 43 (11.7) | 1 | | | | | Serum albumin (g/L) | | | | | <0.001 | | | — | | <35 | 237 (46.9) | 60 (25.3) | 3.2 | 2.0–5.2 | | | | ≥35 | 268 (53.1) | 24 (9.0) | 1.0 | | | | | Serum BChE (U/L) | | | | | <0.001 | | | 0.035 | | ≥4500 | 376 (74.5) | 42 (11.2) | 1 | | 1 | | | <4500 | 129 (25.5) | 42 (32.6) | 3.5 | 2.3–5.3 | 1.8 | 1.0–3.2 |
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BChE: butyrylcholinesterase; BMI: body mass index; HR: hazard ratio; WHO: World Health Organization.
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