Research Article

Circulating CD14+CD163+CD206+ M2 Monocytes Are Increased in Patients with Early Stage of Idiopathic Membranous Nephropathy

Table 1

The demographic and clinical characteristics of participants.

IMN group A IMN group B IMN group C HC

Age, years38 (27–58)45 (28–64)49 (25–60)42 (25–63)
Female/male5/43/56/47/9
Monocytes (109/L)0.3 (0.2–0.45)0.32 (0.21–0.5)0.33 (0.2–0.6)0.35 (0.18–0.35)
Serum uric acid (μmol/L)311 (163–450)363 (300–424)376 (235–499)330 (230–410)
Triglycerides (mmol/L)1.6 (0.6–3.77)2.0 (0.87–5.34)2.1 (1.66–5.26)1.3 (0.42–1.78)
Total cholesterol (mmol/L)6.8 (5.8–13)6.9 (4.4–9)7.4 (4.8–9.1)3.9(2.8–5.6)
Serum albumin (g/L)25 (19.4–39)22 (15–30)21 (17–27)42 (40–52)
Urinary proteins (g/24 h)2 (2–5.3)5.65 (4.4–7) 9.8 (8–11)0.01 (0–0.05)
eGFR (CKD-EPI) (mL/min/1.73 m2)119 (99–127)108 (96–124)99.5 (90–125)118 (102–130)
Serum PLA2R (RU/mL)17.8 (3–76)26 (1.6–77.7)72 (16.9–170)1.5 (0–2.7)

Data shown are median and range. Normal values: monocytes: 0.1–0.6 (109/L), serum uric acid: 155–357 (μmol/L), triglycerides: 0.28–1.8 (mmol/L), total cholesterol (mmol/L): 2.6–6.0 (mmol/L), serum albumin: 40.00–55.00 (g/L), urinary proteins: 0–0.2 (g/24 h), eGFR: 80–120 (mL/min/1.73 m2), and serum PLA2R: 0–14 (RU/mL). IMN: idiopathic membranous nephropathy; HC: healthy control; eGFR: estimated glomerular filtration rate. versus the controls.