Research Article
Circulating CD14+CD163+CD206+ M2 Monocytes Are Increased in Patients with Early Stage of Idiopathic Membranous Nephropathy
Table 1
The demographic and clinical characteristics of participants.
| | IMN group A | IMN group B | IMN group C | HC |
| Age, years | 38 (27–58) | 45 (28–64) | 49 (25–60) | 42 (25–63) | Female/male | 5/4 | 3/5 | 6/4 | 7/9 | Monocytes (109/L) | 0.3 (0.2–0.45) | 0.32 (0.21–0.5) | 0.33 (0.2–0.6) | 0.35 (0.18–0.35) | Serum uric acid (μmol/L) | 311 (163–450) | 363 (300–424) | 376 (235–499) | 330 (230–410) | Triglycerides (mmol/L) | 1.6 (0.6–3.77) | 2.0 (0.87–5.34) | 2.1 (1.66–5.26) | 1.3 (0.42–1.78) | Total cholesterol (mmol/L) | 6.8 (5.8–13) | 6.9 (4.4–9) | 7.4 (4.8–9.1) | 3.9(2.8–5.6) | Serum albumin (g/L) | 25 (19.4–39) | 22 (15–30) | 21 (17–27) | 42 (40–52) | Urinary proteins (g/24 h) | 2 (2–5.3) | 5.65 (4.4–7) | 9.8 (8–11) | 0.01 (0–0.05) | eGFR (CKD-EPI) (mL/min/1.73 m2) | 119 (99–127) | 108 (96–124) | 99.5 (90–125) | 118 (102–130) | Serum PLA2R (RU/mL) | 17.8 (3–76) | 26 (1.6–77.7) | 72 (16.9–170) | 1.5 (0–2.7) |
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Data shown are median and range. Normal values: monocytes: 0.1–0.6 (10 9/L), serum uric acid: 155–357 ( μmol/L), triglycerides: 0.28–1.8 (mmol/L), total cholesterol (mmol/L): 2.6–6.0 (mmol/L), serum albumin: 40.00–55.00 (g/L), urinary proteins: 0–0.2 (g/24 h), eGFR: 80–120 (mL/min/1.73 m 2), and serum PLA2R: 0–14 (RU/mL). IMN: idiopathic membranous nephropathy; HC: healthy control; eGFR: estimated glomerular filtration rate. versus the controls. |