Research Article
Shock Wave Therapy Enhances Mitochondrial Delivery into Target Cells and Protects against Acute Respiratory Distress Syndrome
Figure 2
Mitochondrial functional assay and in vivo showed SW therapy enhanced mitochondrial transfusion into the cells. (a) Mitochondrial functional assay showed a satisfactory activity (i.e., high oxygen consumption rate) of isolated mitochondria (determined by the Mito stress test kit and the XFe24 Analyzer) (). (b, c) Illustrating the confocal findings (400x) of lung specimen at a time interval of 24 h after intravenously mitochondrial transfusion. (d) Analytical results of fluorescent intensity, versus other groups with different symbols (†, ‡), . All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test ( for each group). Symbols (, †, ‡) indicate significance (at 0.05 level). OCR = oxygen consumption rate. ARDS = acute respiratory distress syndrome; Mito = mitochondria; SW = shock wave.
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