Semaphorin 3A Inhibits Inflammation in Chondrocytes under Excessive Mechanical Stress

Figure 2

Change in gene expression patterns under excessive mechanical stress. ATDC5 cells were subjected to excessive CTS for 1, 3, 6, 12, or 24 h. Gene expression levels of IL-1β, TNF-α, COX-2, MMP-3, and MMP-13 at each time point were determined by qPCR analysis (a–e). Data are expressed as mean ± SD, . , compared to controls at each time point.

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