Research Article

Activation of GABAB Receptor Suppresses Diabetic Neuropathic Pain through Toll-Like Receptor 4 Signaling Pathway in the Spinal Dorsal Horn

Table 1

Comparison of mechanical paw withdrawal threshold (in grams, , mean ± SE) in rats.

GroupBaseline7 days14 days21 days

Control14.17 ± 2.8513.87 ± 2.5814.86 ± 2.6914.26 ± 2.63
DNP14.86 ± 2.3312.42 ± 1.924.78 ± 1.45,4.28 ± 1.45,
LPS-RS + DNP13.88 ± 3.0311.89 ± 3.224.82 ± 1.32,4.42 ± 1.38,
SN50 + DNP14.98 ± 1.9813.12 ± 2.764.67 ± 1.21,4.51 ± 1.55,
MIP + DNP15.07 ± 2.4212.32 ± 2.974.77 ± 1.44,4.62 ± 1.48,
Baclofen + DNP14.55 ± 2.6613.65 ± 3.485.14 ± 1.53,4.84 ± 1.50,

Compared with baseline values, . Compared with the control group, .