Research Article
Activation of GABAB Receptor Suppresses Diabetic Neuropathic Pain through Toll-Like Receptor 4 Signaling Pathway in the Spinal Dorsal Horn
Table 2
Comparison of thermal paw withdrawal latency (in seconds,
, mean ± SE) in rats.
| Group | Baseline | 7 days | 14 days | 21 days |
| Control | 15.6 ± 2.8 | 115.8 ± 2.9 | 15.7 ± 2.7 | 15.9 ± 2.6 | DNP | 15.8 ± 3.5 | 111.8 ± 3.5 | 8.4 ± 2.5, | 7.8 ± 1.7, | LPS-RS + DNP | 16.9 ± 3.3 | 112.6 ± 3.9 | 7.9 ± 1.9, | 7.2 ± 2.0, | SN50 + DNP | 16.2 ± 2.9 | 113.5 ± 4.0 | 8.2 ± 2.1, | 7.5 ± 2.1, | MIP + DNP | 15.9 ± 2.6 | 112.9 ± 3.8 | 7.7 ± 1.6, | 7.7 ± 2.3, | Baclofen + DNP | 16.5 ± 3.8 | 113.3 ± 4.4 | 8.1 ± 2.2, | 7.9 ± 1.6, | Saclofen + DNP | 15.5 ± 2.7 | 112.7 ± 3.6 | 7.5 ± 1.8, | 7.2 ± 2.2, |
|
|
Compared with baseline values, . Compared with the control group, . |