Table of Contents Author Guidelines Submit a Manuscript
Mediators of Inflammation
Volume 2018 (2018), Article ID 6148351, 9 pages
https://doi.org/10.1155/2018/6148351
Research Article

Calophyllum brasiliense Modulates the Immune Response and Promotes Leishmania amazonensis Intracellular Death

1Graduate Program in Bioscience and Physiopathology, Departamento de Análises Clínicas e Biomedicina, The State University of Maringá, Colombo Avenue 5790, 87020-900 Maringá, PR, Brazil
2Departamento de Análises Clínicas e Biomedicina, The State University of Maringá, Maringá, PR, Brazil
3Postgraduate Program in Health Sciences, Centro de Ciências da Saúde, State University of Maringá, Maringá, PR, Brazil

Correspondence should be addressed to I. G. Demarchi

Received 19 October 2017; Accepted 18 December 2017; Published 13 February 2018

Academic Editor: Elaine Hatanaka

Copyright © 2018 L. Domeneghetti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Brasil, Ministério da Saúde, Manual de Vigilância da Leishmaniose Tegumentar Americana, Editora do Ministério da Saúde, Brasília, Brazil, 2 edition, 2007.
  2. W. N. Oliveira, L. E. Ribeiro, A. Schrieffer, P. Machado, E. M. Carvalho, and O. Bacellar, “The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of human tegumentary leishmaniasis,” Cytokine, vol. 66, no. 2, pp. 127–132, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. WHO, World Health Organization. Control of the Leishmaniasis: Report of a Meeting of the WHO. Expert Committee on the Control of Leihmaniases. “WHO Technical Report Series”, World Health Organization, Geneva, Switzerland, 2010, 949.
  4. K. J. Gollob, A. G. Viana, and W. O. Dutra, “Immunoregulation in human American leishmaniasis: balancing pathology and protection,” Parasite Immunology, vol. 36, no. 8, pp. 367–376, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. WHO, World Health Organization, “Control of the Leishmaniasis: Report of a Meeting of the WHO Expert Committee on the Control of Leishmaniases,” WHO Technical Report Series, World Health Organization, Geneva, Switzerland, 2010.
  6. A. Machado-Silva, P. P. Guimarães, C. A. Tavares, and R. D. Sinisterra, “New perspectives for leishmaniasis chemotherapy over current anti-leishmanial drugs: a patent landscape,” Expert Opinion on Therapeutic Patents, vol. 25, no. 3, pp. 247–260, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Iriti, S. Vitalini, G. Fico, and F. Faoro, “Neuroprotective herbs and foods from different traditional medicines and diets,” Molecules, vol. 15, no. 5, pp. 3517–3555, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. P. M. Cheuka, G. Mayoka, P. Mutai, and K. Chibale, “The role of natural products in drug discovery and development against neglected tropical diseases,” Molecules, vol. 22, no. 1, article E58, 2017. View at Publisher · View at Google Scholar · View at Scopus
  9. V. C. Filho, C. Meyre-Silva, and R. Niero, “Chemical and pharmacological aspects of the genus Calophyllum,” Chemistry & Biodiversity, vol. 6, no. 3, pp. 313–327, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. B. M. Cardoso, T. F. De Mello, D. S. Lera et al., “Antileishmanial activity of Calophyllum brasiliense leaf extract,” Planta Medica, vol. 83, no. 01/02, pp. 57–62, 2017. View at Publisher · View at Google Scholar · View at Scopus
  11. M. A. Brenzan, C. V. Nakamura, B. P. D. Filho, T. Ueda-Nakamura, M. C. Young, and D. A. G. Cortez, “Antileishmanial activity of crude extract and coumarin from Calophyllum brasiliense leaves against Leishmania amazonensis,” Parasitology Research, vol. 101, no. 3, pp. 715–722, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. M. A. Brenzan, A. O. Santos, C. V. Nakamura et al., “Effects of (−) mammea a/BB isolated from Calophyllum brasiliense leaves and derivatives on mitochondrial membrane of Leishmania amazonensis,” Phytomedicine, vol. 19, no. 3-4, pp. 223–230, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. P. A. Honda, I. C. P. Ferreira, D. A. G. Cortez et al., “Efficacy of components from leaves of Calophyllum brasiliense against Leishmania (Leishmania) amazonensis,” Phytomedicine, vol. 17, no. 5, pp. 333–338, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. C. M. O. Simões, E. P. Schenkel, G. Gosmann, J. C. P. Mello, L. A. Mentz, and P. R. Petrovick, Farmacognosia: da Planta ao Medicamento, Editora da Universidade UFRGS, Porto Alegre/Florianópolis, 2002.
  15. H. Lorenzi, Árvores Brasileiras: Manual de Identificação e Cultivo de Plantas Arbóreas Nativas do Brasil, vol. 352, Instituto Plantarum, Nova Odessa: Plantarum, 1992.
  16. M. C. M. Marques and C. A. Joly, “Germinação e crescimento de Calophyllum brasiliense (Clusiaceae), uma espécie típica de florestas inundadas,” Acta Botanica Brasilica, vol. 14, no. 1, pp. 113–120, 2000. View at Publisher · View at Google Scholar · View at Scopus
  17. L. C. Klein-Júnior, D. Zambiasi, G. R. Salgado, F. Delle Monache, V. C. Filho, and F. de Campos Buzzi, “The validation of Calophyllum brasiliense (“guanandi”) uses in Brazilian traditional medicine as analgesic by in vivo antinociceptive evaluation and its chemical analysis,” Naunyn-Schmiedeberg’s Archives of Pharmacology, vol. 390, no. 7, pp. 733–739, 2017. View at Publisher · View at Google Scholar · View at Scopus
  18. T. V. Lordani, M. A. Brenzan, L. E. Cortez et al., “Effect of a topical formulation containing Calophyllum brasiliense Camb. extract on cutaneous wound healing in rats,” Natural Product Research, vol. 29, no. 10, pp. 953–957, 2015. View at Publisher · View at Google Scholar · View at Scopus
  19. C. Ruiz-Marcial, R. Reyes Chilpa, E. Estrada, J. Reyes-Esparza, G. G. Fariña, and L. Rodríguez-Fragoso, “Antiproliferative, cytotoxic and antitumour activity of coumarins isolated from Calophyllum brasiliense,” The Journal of Pharmacy and Pharmacology, vol. 59, no. 5, pp. 719–725, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. T. Blanco-Ayala, R. Lugo-Huitrón, E. M. Serrano-López et al., “Antioxidant properties of xanthones from Calophyllum brasiliense: prevention of oxidative damage induced by FeSO4,” BMC Complementary and Alternative Medicine, vol. 13, no. 1, p. 262, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. F. Abe, S. Nagafuji, and H. Okabe, “Trypanocidal constituents in plants 3. Leaves of Garcinia intermedia and heartwood of Calophyllum brasiliense,” Biological & Pharmaceutical Bulletin, vol. 27, no. 1, pp. 141–143, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. V. F. Noldin, D. B. Isaias, and V. C. Filho, “Gênero Calophyllum: importância química e farmacológica,” Química Nova, vol. 29, no. 3, pp. 549–554, 2006. View at Publisher · View at Google Scholar · View at Scopus
  23. C. T. Pires, R. B. d. L. Scodro, M. A. Brenzan et al., “Anti-Mycobacterium tuberculosis activity of Calophyllum brasiliense extracts obtained by supercritical fluid extraction and conventional techniques,” Current Pharmaceutical Biotechnology, vol. 17, no. 6, pp. 532–539, 2016. View at Publisher · View at Google Scholar
  24. C. T. Pires, M. A. Brenzan, R. B. Scodro et al., “Anti-Mycobacterium tuberculosis activity and cytotoxicity of Calophyllum brasiliense Cambess (Clusiaceae),” Memórias do Instituto Oswaldo Cruz, vol. 109, no. 3, pp. 324–329, 2014. View at Publisher · View at Google Scholar · View at Scopus
  25. J. B. Pretto, V. Cechinel-Filho, V. F. Noldin, M. R. Sartori, D. E. Isaias, and A. B. Cruz, “Antimicrobial activity of fractions and compounds from Calophyllum brasiliense (Clusiaceae/Guttiferae),” Zeitschrift fur Naturforschung C, vol. 59, no. 9-10, pp. 657–662, 2004. View at Google Scholar
  26. S. Kimura, C. Ito, N. Jyoko et al., “Inhibition of leukemic cell growth by a novel anti-cancer drug (GUT-70) from Calophyllum brasiliense that acts by induction of apoptosis,” International Journal of Cancer, vol. 113, no. 1, pp. 158–165, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Huerta-Reyes, M. C. Basualdo, F. Abe, M. Jimenez-Estrada, C. Soler, and R. Reyes-Chilpa, “HIV-1 inhibitory compounds from Calophyllum brasiliense leaves,” Biological and Pharmaceutical Bulletin, vol. 27, no. 9, pp. 1471–1475, 2004. View at Publisher · View at Google Scholar · View at Scopus
  28. I. G. Demarchi, M. V. Thomazella, M. de Souza Terron et al., “Antileishmanial activity of essential oil and 6,7-dehydroroyleanone isolated from Tetradenia riparia,” Experimental Parasitology, vol. 157, pp. 128–137, 2015. View at Publisher · View at Google Scholar · View at Scopus
  29. L. N. Prista, A. A. Correia, and R. Morgado, Técnica Farmacêutica e Farmácia Galênica, Fundação Calouste Gulbenkian, Lisboa, 4 edition, 1996.
  30. I. G. Demarchi, M. De Souza Terron, M. V. Thomazella et al., “Antileishmanial and immunomodulatory effects of the essential oil from Tetradenia riparia (Hochstetter) Codd,” Parasite Immunology, vol. 38, no. 1, pp. 64–77, 2016. View at Publisher · View at Google Scholar · View at Scopus
  31. H. Kolodziej, A. Burmeister, W. Trun et al., “Tannins and related compounds induce nitric oxide synthase and cytokines gene expressions in Leishmania major-infected macrophage-like RAW 264.7 cells,” Bioorganic & Medicinal Chemistry, vol. 13, no. 23, pp. 6470–6476, 2005. View at Publisher · View at Google Scholar · View at Scopus
  32. T. Chen, X. Zhao, Y. Liu, Q. Shi, Z. Hua, and P. Shen, “Analysis of immunomodulating nitric oxide, iNOS and cytokines mRNA in mouse macrophages induced by microcystin-LR,” Toxicology, vol. 197, no. 1, pp. 67–77, 2004. View at Publisher · View at Google Scholar · View at Scopus
  33. S. N. Byrne, C. Beaugie, C. O’Sullivan, S. Leighton, and G. M. Halliday, “The immune-modulating cytokine and endogenous alarmin Interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation,” The American Journal of Pathology, vol. 179, no. 1, pp. 211–222, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. B. Monge-Maillo and R. Lopez-Velez, “Therapeutic options for Old World cutaneous leishmaniasis and New World cutaneous and mucocutaneous leishmaniasis,” Drugs, vol. 73, no. 17, pp. 1889–1920, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. K. R. Gantt, T. L. Goldman, M. L. McCormick et al., “Oxidative responses of human and murine macrophages during phagocytosis of Leishmania chagasi,” The Journal of Immunology, vol. 167, no. 2, pp. 893–901, 2001. View at Publisher · View at Google Scholar
  36. S. O. Amoo, A. O. Aremu, M. Moyo, and J. Van Staden, “Antioxidant and acetylcholinesterase-inhibitory properties of long-term stored medicinal plants,” BMC Complementary and Alternative Medicine, vol. 12, no. 1, p. 87, 2012. View at Publisher · View at Google Scholar · View at Scopus
  37. C. Dye, “The logic of visceral leishmaniasis control,” The American Journal of Tropical Medicine and Hygiene, vol. 55, no. 2, pp. 125–130, 1996. View at Publisher · View at Google Scholar
  38. E. Pinelli, R. M. Gonzalo, C. J. Boog et al., “Leishmania infantum-specific T cell lines derived from asymptomatic dogs that lyse infected macrophages in a major histocompatibility complex-restricted manner,” European Journal of Immunology, vol. 25, no. 6, pp. 1594–1600, 1995. View at Publisher · View at Google Scholar · View at Scopus
  39. G. A. Duque, M. Fukuda, S. J. Turco, S. Stager, and A. Descoteaux, “Leishmania promastigotes induce cytokine secretion in macrophages through the degradation of synaptotagmin XI,” Journal of Immunology, vol. 193, no. 5, pp. 2363–2372, 2014. View at Publisher · View at Google Scholar · View at Scopus
  40. P. R. L. Machado, L. Carvalho, M. I. A. S. Araújo, and E. M. Carvalho, “Mecanismos de resposta imune às infecções,” Anais Brasileiros de Dermatologia, vol. 79, no. 6, pp. 647–662, 2004. View at Publisher · View at Google Scholar
  41. Y. Li, K. Ishii, H. Hisaeda et al., “IL-18 gene therapy develops Th1-type immune responses in Leishmania major-infected BALB/c mice: is the effect mediated by the CpG signaling TLR9?” Gene Therapy, vol. 11, no. 11, pp. 941–948, 2004. View at Publisher · View at Google Scholar · View at Scopus
  42. T. T. Espir, L. de Paula Figueira, M. de Farias Naiff et al., “The role of inflammatory, anti-inflammatory, and regulatory cytokines in patients infected with cutaneous leishmaniasis in Amazonas state, Brazil,” Journal of Immunology Research, vol. 2014, Article ID 481750, 10 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  43. L. P. Carvalho, M. Soto, and S. Jerônimo, “Characterization of the immune response to Leishmania infantum recombinant antigens,” Microbes and Infection, vol. 5, no. 1, pp. 7–12, 2003. View at Publisher · View at Google Scholar · View at Scopus
  44. D. S. Lima-Junior, D. L. Costa, V. Carregaro et al., “Inflammasome-derived IL-1beta production induces nitric oxide-mediated resistance to Leishmania,” Nature Medicine, vol. 19, no. 7, pp. 909–915, 2013. View at Publisher · View at Google Scholar · View at Scopus
  45. D. R. Neill, S. H. Wong, A. Bellosi et al., “Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity,” Nature, vol. 464, no. 7293, pp. 1367–1370, 2010. View at Publisher · View at Google Scholar · View at Scopus