Diabetes Downregulates Allergen-Induced Airway Inflammation in Mice

Table 1

Alloxan-induced diabetes causes hyperglycemia, loss of body weight, hypoinsulinemia, and hypercorticoidism.

Group	Glycemia (mmol/L)	Body weight (g)	Plasma insulin (μU/mL)	Plasma corticosterone (ng/mL)
Nondiabetic	6 ± 0.5	36 ± 1	36 ± 7	56 ± 16
Diabetic	23 ± 0.8^+++	27 ± 1^+++	8 ± 2^++	358 ± 44^+++

Diabetes was induced by a single intravenous injection of alloxan (65 mg/kg) and the analyses performed 27 days after diabetes induction. Values represent mean ± SEM of 6 animals. compared to nondiabetic mice. compared to nondiabetic mice.