Resveratrol Suppresses Gut-Derived NLRP3 Inflammasome Partly through Stabilizing Mast Cells in a Rat Model

<div>Resveratrol pretreatment inhibited NLRP3 inflammasome activation by stabilizing mast cells. (a) Representative western blotting bands of NLRP3, caspase-1 p20, IL-1<i>β</i> p17, and IL-18 for each group. (b) NLRP3 protein expression level. (c) Caspase-1 p20 protein expression level. (d) IL-1<i>β</i> p17 protein expression level. (e) IL-18 protein expression level. IIR: intestinal ischemia-reperfusion; RESV: resveratrol; CP: compound 48/80; CS: cromolyn sodium. 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Mediators of Inflammation

fig3

Figure 3

Figure 3: Resveratrol Suppresses Gut-Derived NLRP3 Inflammasome Partly through Stabilizing Mast Cells in a Rat Model 