Aspirin Disrupts the Crosstalk of Angiogenic and Inflammatory Cytokines between 4T1 Breast Cancer Cells and Macrophages

Figure 3

The effect of aspirin on viability of 4T1 cells cultured in RAW-CM. Different doses of aspirin were used to treat 4T1 cells cultured in 50% unstimulated or LPS-stimulated RAW-CM. Cells were cultured for (a) 24 or (b) 72 h, and cell viability was assessed using MTT assays. Data are shown as mean ± SEM and are from three independent experiments. Statistical analysis was performed using one-way ANOVA and LSD post hoc tests. , , and versus vehicle control.

(a)

(b)