Prevalence and Determinants of Peripheral Microvascular Endothelial Dysfunction in Rheumatoid Arthritis Patients: A Multicenter Cross-Sectional Study
Table 4
Independent determinants of Ln-RHI.
Independent variable
Bivariate correlation Spearman rho
Univariate linear regression B coefficient (95% IC)
Multiple linear regression B coefficient (95% IC)
Systolic blood pressure (mmHg)
0.10
0.002 (0.001–0.003)
0.003 (0.001–0.004)
ACPA positivity
0.10
0.054 (0.006–0.102)∧
0.089 (0.035–0.144)
Smoke habit
−0.10
−0.078 (from −0.132 to −0.025)
−0.085 (−0.153–0.017)∧
Dyslipidemia
0.08∧
0.060 (0.008–0.111)∧
BMI
−0.086∧
HDL cholesterol (mg/dL)
0.073
0.001 (0.000–0.003)∧
0.002 (0.000–0.004)∧
Triglycerides (mg/dL)
−0.07∧
−0.001 (from −0.001 to –0.000)∧
Disease duration
−0.06∧
A linear regression for multiple variables (stepwise method) was performed including into the model variables showing significant association () with the dependent variable Ln-RHI at the univariate regression analysis. Age and gender were forced in the model. ,.
