Prevalence and Determinants of Peripheral Microvascular Endothelial Dysfunction in Rheumatoid Arthritis Patients: A Multicenter Cross-Sectional Study

Table 5

Independent determinants of peripheral ED.

	ED	No ED	Binary logistic analysis OR (95% IC)	Multivariate logistic analysis OR (95% IC)	Cox and Snell R^2
Systolic blood pressure (mmHg)	125.4 ± 15.5	129 ± 17.1	0.98 (0.97–0.99)^a	0.98 (0.97–0.99)^a	0.04
Triglycerides (mg/dL)	103.7 ± 48.2	95.4 ± 42.7	1.004 (1.001–1.007)^b^∧	1.005 (1.002–1.009)^b
ACPA negativity [n (%)]	44.1	33.8	1.546 (1.126–2.122)	1.708 (1.218–2.396)
Smoking habit [n (%)]	25.2	18.6	1.468 (1.047–2.059)^∧	—
Diastolic blood pressure (mmHg)	75.9 ± 8.9	77.4 ± 10.2	0.98 (0.97–0.99)^∧	—
BMI (kg/m^2)	29.5 ± 32.5	27.9 ± 34.4	—	—
Disease duration (months)	141.2 ± 116.8	127.1 ± 115.8	—	—

Odds ratio (OR) is based on the risk of the dependent variable (low Ln-RHI) given the presence of the independent variable. 95% CI: 95% confidence interval. Multivariate logistic analysis with backward logistic regression method has been performed including in the model variables showing significant () association with the dependent variable (low Ln-RHI) at the binary logistic analysis. ; ; ^aper mmHg; ^bper mg/dL.