Apoptosis-Associated Speck-Like Protein Containing a CARD Deletion Ameliorates Unilateral Ureteral Obstruction Induced Renal Fibrosis and Endoplasmic Reticulum Stress in Mice
ASC deletion attenuates UUO-induced renal fibrotic cytokines in mice. (a) Representative photomicrographs at 14 days after UUO of collagen I staining (magnification, ×400). (b) Representative photomicrographs at 14 days after UUO of fibronectin staining (magnification, ×400). (c) Semiquantitative analysis of collagen I among the different groups. (d) Quantification of fibronectin-positive areas. , WT/sham group versus WT/UUO group. , ASC−/−/UUO group versus WT/UUO group. Data represent the mean ± SEM ().