Mediators of Inflammation / 2018 / Article / Fig 7

Research Article

Apoptosis-Associated Speck-Like Protein Containing a CARD Deletion Ameliorates Unilateral Ureteral Obstruction Induced Renal Fibrosis and Endoplasmic Reticulum Stress in Mice

Figure 7

Activation of ER stress induced by UUO is inhibited by ASC deficiency. (a) Immunoblotting for the levels of BIP, p-eIF2α/eIF2α, ATF4, and CHOP. (b) Quantification analysis of BIP, p-eIF2α/eIF2α, ATF4, and CHOP levels, normalized against those of β-actin. , WT/sham group versus WT/UUO group. , ASC−/−/UUO group versus WT/UUO group. Data represent the mean ± SEM ().