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Mediators of Inflammation
Volume 2018, Article ID 7354250, 12 pages
https://doi.org/10.1155/2018/7354250
Review Article

Therapeutic Effects of Medicinal Plants on Cutaneous Wound Healing in Humans: A Systematic Review

1Postgraduate Program in Bioscience and Pathophysiology, Universidade Estadual de Maringá, Avenida Colombo 5790, Jardim Universitário, 87020-900 Maringá, PR, Brazil
2Postgraduate Program in Health Sciences, Universidade Estadual de Maringá, Avenida Colombo 5790, Jardim Universitário, 87020-900 Maringá, PR, Brazil
3Department of Clinical Nutrition, Universidade Estadual do Oeste do Paraná, Rua Universitária 1619, Universitário, 85819-110 Cascavel, PR, Brazil
4Medical and Pharmaceutical Science Center, Universidade Estadual do Oeste do Paraná, Rua Universitária 1619, Universitário, 85819-110 Cascavel, PR, Brazil
5Department of Clinical Analysis and Biomedicine, Universidade Estadual de Maringá, Avenida Colombo 5790, Jardim Universitário, 87020-900 Maringá, PR, Brazil

Correspondence should be addressed to Tarcisio Vitor Augusto Lordani; moc.liamtoh@inadroloisicrat

Received 29 September 2017; Accepted 2 January 2018; Published 1 April 2018

Academic Editor: Giuseppe Valacchi

Copyright © 2018 Tarcisio Vitor Augusto Lordani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The pharmaceutical industry has made great strides in providing drugs that are able to stimulate the healing process, but only 1–3% of all drugs that are listed in Western pharmacopoeias are intended for use on the skin or cutaneous wounds. Of these, at least one-third are obtained from plants. We sought to review the therapeutic effects of medicinal plants on human skin lesions. For this systematic review, we searched the PubMed, Scopus, and Web of Science databases to identify clinical trials that were published from 1997 to 2017. We reviewed studies that described the use of medicinal plants for the treatment of skin lesions in humans. Ten studies were selected, eight of which were published from 2007 to 2016, with a total of 503 patients. Among the plant species that were used for the treatment of human skin lesions, 12 belonged to 11 families and were included in the analysis. All of the plant species that were studied presented high therapeutic potential for the treatment of cutaneous lesions.