Research Article
Long Noncoding RNAs and mRNA Regulation in Peripheral Blood Mononuclear Cells of Patients with Chronic Obstructive Pulmonary Disease
Table 9
The selected predicted regulation of dysregulated lncRNAs on mRNAs in COPD patients compared to smokers.
| | lncRNA | Gene symbol | Target gene | Microarray analyze fold change | Function |
| | NR_026891.1 | FLJ10038 | CXCL16 | 2.29 | Induced by the inflammatory cytokines IFN-gamma and TNF-alpha; cytokine-cytokine receptor interaction, organism-specific biosystem | | ENST00000502883.1 | RP11-499E18.1 | CXCL16 | 2.29 | Induced by the inflammatory cytokines IFN-gamma and TNF-alpha; cytokine-cytokine receptor interaction, organism-specific biosystem | | HIT000648516 | — | HMOX1 | 2.71 | Keap1-Nrf2 pathway, organism-specific biosystem | | XR_429541.1 | — | SLA2 | 0.46 | Negative regulation of B cell activation; regulation of immune response
TCR signaling in naive CD4+ T cells | | ENST00000597550.1 | CTD-2245F17.3 | SIGLEC14 | 2.57 | Innate immune system
Cell adhesion |
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