Research Article
Markers of Glomerular and Tubular Damage in the Early Stage of Kidney Disease in Type 2 Diabetic Patients
Table 4
Correlations between studied serum and urine markers and eGFR, diabetes duration, and HbA1c concentrations.
| Marker | eGFR (CKD-EPICr) | Diabetes duration | HbA1c | uACR | | value | | value | | value | | value |
| Serum cystatin C | −0.72 | <0.001# | 0.17 | 0.1 | −0.05 | 0.7 | 0.21 | 0.08 | Urine albumin | 0.02 | 0.9 | 0.21 | 0.071 | 0.28 | 0.020# | NA | Urine albumin/creatinine | −0.01 | 0.9 | 0.25 | 0.037# | 0.29 | 0.015# | NA | Serum NGAL | −0.15 | 0.2 | 0.09 | 0.4 | 0.10 | 0.4 | 0.13 | 0.3 | Urine NGAL | −0.06 | 0.6 | 0.19 | 0.1 | 0.24 | 0.048# | 0.39 | <0.001# | Urine NGAL/creatinine | −0.05 | 0.7 | 0.24 | 0.046# | 0.25 | 0.035# | 0.36 | 0.002# | Urine KIM-1 | 0.11 | 0.4 | −0.03 | 0.8 | 0.08 | 0.5 | 0.32 | 0.005# | Urine KIM-1/creatinine | 0.05 | 0.7 | 0.05 | 0.7 | 0.16 | 0.2 | 0.45 | <0.001# | Urine transferrin | −0.17 | 0.1 | 0.19 | 0.1 | 0.32 | 0.006# | 0.48 | <0.001# | Urine IgG | −0.14 | 0.2 | 0.27 | 0.016# | 0.33 | 0.005# | 0.61 | <0.001# | Serum uromodulin | 0.16 | 0.2 | 0.06 | 0.6 | 0.03 | 0.8 | −0.09 | 0.4 | Urine uromodulin | 0.08 | 0.5 | −0.14 | 0.2 | −0.35 | 0.002# | −0.03 | 0.8 | Urine uromodulin/creatinine | 0.04 | 0.7 | −0.12 | 0.3 | −0.32 | 0.009# | 0.01 | 0.9 |
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#Statistically significant correlation. Abbreviations: see Table 1; NA: not applicable. |