Mediators of Inflammation / 2018 / Article / Tab 1 / Research Article
Mast Cells Exert Anti-Inflammatory Effects in an IL10−/− Model of Spontaneous Colitis Table 1 Mast cell deficiency results in dysregulation of many different cytokines and chemokines. Fold change and
value of DKO and DKO-rMC mice compared to IL10
−/− . Significantly upregulated genes and downregulated genes indicated by bold and italic font, respectively (
).
Fold change and DKO DKO-rMC Fold change Fold change Adipoq 0.93 0.605923 0.44 0.12537 Bmp2 0.36 0.00275 0.43 0.00352 Bmp4 0.47 0.003545 0.78 0.08664 Bmp6 0.38 0.027679 0.71 0.12534 Bmp7 0.55 0.0662 0.77 0.13341 Ccl1 2.3 0.06215 1.71 0.20753 Ccl11 0.54 0.157722 0.79 0.31294 Ccl12 0.46 0.020304 1.11 0.57195 Ccl17 1.12 0.862792 1.05 0.85839 Ccl19 1.4 0.281436 1.24 0.4384 Ccl2 1.46 0.268872 1.33 0.25702 Ccl20 0.84 0.90886 1.09 0.73897 Ccl22 1.23 0.36045 0.79 0.52381 Ccl24 0.86 0.287519 0.55 0.02211 Ccl3 2.5 0.304203 1.62 0.10923 Ccl4 3.6 0.132224 2.05 0.00244 Ccl5 5.19 0.059787 2.87 0.02972 Ccl7 1.27 0.259336 1.22 0.24594 Cd40lg 2.54 0.035975 2.89 0.01671 Cd70 0.94 0.73583 0.74 0.21501 Cntf 1.05 0.869816 0.79 0.11255 Csf1 0.54 0.011483 0.66 0.10244 Csf2 1.77 0.337615 1.28 0.73852 Csf3 1.93 0.18316 0.95 0.98266 Ctf1 0.49 0.131314 1.13 0.73413 Cx3cl1 0.57 0.024194 0.69 0.14404 Cxcl1 2.65 0.164314 1.48 0.2263 Cxcl10 1.69 0.232777 1.05 0.94321 Cxcl11 1.39 0.368579 0.96 0.96597 Cxcl12 0.44 0.009886 0.71 0.07872 Cxcl13 1.31 0.421716 1.09 0.73564 Cxcl16 1.02 0.830846 0.89 0.42328 Cxcl3 7.7 0.169696 0.95 0.91528 Cxcl5 3.37 0.212199 0.94 0.88692 Cxcl9 5.89 0.078554 3.3 0.06285 Fasl 3.09 0.119071 2.03 0.04219 Gpi1 1.07 0.640631 1.02 0.97433 Hc 0.75 0.681503 1.62 0.1135 Ifna2 0.93 0.605923 0.44 0.12537 Ifng 5.15 0.143744 2.21 0.13276 Il10 0.93 0.605923 0.44 0.12537 Il11 2.39 0.165436 1 0.82803 Il12a 0.54 0.098954 0.61 0.09123 Il12b 1.47 0.256595 1.62 0.12956 Il13 1.09 0.651106 1 0.99484 Il15 0.53 0.016916 0.73 0.07861 Il16 1.01 0.896996 0.56 0.04287 Il17a 1.12 0.484613 0.35 0.08594 Il17f 0.68 0.282624 0.55 0.00207 Il18 0.46 0.070874 0.87 0.26885 Il1a 3.9 0.220118 0.9 0.65997 Il1b 3.96 0.172113 1.26 0.38028 Il1rn 0.7 0.006867 0.73 0.03971 Il2 0.94 0.639082 0.48 0.13164 Il21 1.6 0.306708 0.44 0.12537 Il22 1.87 0.268256 0.54 0.12908 Il23a 0.8 0.611696 0.89 0.47794 Il24 1.45 0.684595 0.47 0.13168 Il27 1.45 0.322021 1.28 0.68824 Il3 1.06 0.871143 0.44 0.12537 Il4 1.67 0.323998 2.15 0.02924 Il5 0.73 0.547827 0.66 0.31967 Il6 3.97 0.227976 1.21 0.40714 Il7 0.48 0.180451 0.68 0.13566 Il9 0.93 0.605923 0.55 0.16928 Lif 1.11 0.576603 0.51 0.01984 Lta 0.65 0.44487 0.55 0.6218 Ltb 1.55 0.23314 0.83 0.91681 Mif 1.17 0.107953 1.18 0.29987 Mstn 1.13 0.736482 0.59 0.21285 Nodal 0.93 0.605923 0.52 0.15365 Osm 5.53 0.119627 1.56 0.12463 Pf4 0.47 0.030614 0.63 0.05057 Ppbp 1.14 0.986882 1.54 0.55059 Spp1 4.12 0.261256 1.77 0.93377 Tgfb2 0.51 0.048987 0.77 0.12043 Thpo 1.11 0.432272 1 0.80533 Tnf 2.54 0.151012 1.3 0.2214 Tnfrsf11b 0.91 0.948453 0.92 0.89644 Tnfsf10 1.16 0.779851 1.05 0.97127 Tnfsf11 2.2 0.211322 0.96 0.64542 Tnfsf13b 0.92 0.651414 0.93 0.44799 Vegfa 1.12 0.747986 0.92 0.55534 Xcl1 1.1 0.9224 1.28 0.48461
