Serum Levels of IL-33 and Correlation with IL-4, IL-17A, and Hypergammaglobulinemia in Patients with Autoimmune Hepatitis

Figure 5

Serum levels of IL-33 in EAIH mice. Ten mice (5 from the EAIH group and 5 from the control group) were killed at each time point (7, 14, and 28 days). (a) Representative histological image of liver lesions in animals after standard induction of EAIH (magnification, 100x). (b) Serum ALT levels were progressively upregulated from 1 to 28 days. (c) Serum AST levels were progressively upregulated from 1 to 28 days. (d) Histological score of liver lesions in mice after standard induction of EAIH. (e) Serum IL-33 levels were progressively upregulated from 1 to 28 days. Data shown are the mean levels of serum IL-33 in each mouse from two separate experiments. The horizontal lines indicate the mean values for the different groups. ; .

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