Serum Levels of IL-33 and Correlation with IL-4, IL-17A, and Hypergammaglobulinemia in Patients with Autoimmune Hepatitis
Table 1
Demographic and clinical characteristics of study participants.
Parameters
AIH patients
HCs
Number
30
20
Age (years)
49 (38–76)
51 (41–74)
Gender: female/male
22/8
14/6
ALT (U/L)
126.4 ± 111.9
27.2 ± 8.2
AST (U/L)
102.4 ± 55.3
22.7 ± 5.7
γ-GT (U/L)
88.9 ± 31.4
25.1 ± 7.4
ALP (U/L)
132.6 ± 36.8
89.5 ± 23.6
Anti-ANA(+)
23/30 (76.7%)
0/20 (0%)
Anti-ANA titer
1 : 640 (1 : 80–1 : 10000)
—
Anti-SMA(+)
2/30 (6.7%)
0/20 (0%)
Anti-SMA titer
1 : 1000 (1 : 160–1 : 3200)
—
IgG (g/L)
15.8 ± 3.8
7.8 ± 2.3
IgM (g/L)
6.8 ± 1.9
2.64 ± 0.87
IgA (g/L)
3.98 ± 2.2
1.6 ± 1.1
WBC count (109/L)
7.62 (5.6–11.2)
5.08 (3.9–9.2)
Data shown are expressed as mean ± SD. Normal values: ALT: <40 IU/L; AST: <40 IU/L; ANA: <1 : 80; SNA: <1 : 80. IgG: normal range = 7–16 g/L; IgM: normal range = 0.7–4.6 g/L; IgA: normal range = 0.4–2.3 g/L. HC: healthy control; AIH: autoimmune hepatitis. versus HC.
