Research Article

Fecal Galectin-3: A New Promising Biomarker for Severity and Progression of Colorectal Carcinoma

Table 2

Correlation between the fecal level of Gal-3 and parameters of disease severity and progression in patients with CRC and UC. Statistical significance was tested by Spearman correlation coefficient.

VariablesGal-3
Spearman’s rho value

CRC
 Nuclear grade0.3580.025
 Histological type0.5430.001
 Dukes stage0.3390.035
 Liver metastasis0.4060.004
 Lung metastasis0.3030.036
 Peritoneal carcinomatosis0.4200.003
 AFP0.4380.002
 CEA0.3080.049
 CA19-90.2540.088

UC
 Endoscopic score0.1870.172
 Clinical score0.0910.511
 Crypt destruction0.1930.159
 Erosion of the mucous membranes0.1700.215
 Architectural changes0.1000.468
 Neutrophil infiltration0.1070.435
 Eosinophil infiltration0.0350.799