Research Article

The Protective Effect of Naringenin on Airway Remodeling after Mycoplasma Pneumoniae Infection by Inhibiting Autophagy-Mediated Lung Inflammation and Fibrosis

Table 1

Characteristics of subjects in the study.

Demographic characteristicsNon-Mycoplasma pneumoniae () (%)Mycoplasma pneumoniae () (%)

Sex
Female34 (53%)38 (63%)
Male30 (47%)22 (37%)
Age
1–3 years5 (7.8%)4 (6.7%)
3–7 years41 (64.1%)32 (53.3%)
7–14 years18 (28.1%)24 (40%)
Average age6.51 ± 2.857.01 ± 2.80
Whole blood cell analysis
White blood cell (×109)10.82 ± 2.3811.23 ± 3.24
Neutrophils (%)28.79 ± 13.2437.38 ± 12.68
Lymphocytes (%)61.28 ± 14.2657.36 ± 16.38
Blood platelet (×109)375.9 ± 132.7399.8 ± 142.8
Expression of mammary immune-associated factors
IL-1β (pg/ml)23.67 ± 6.3567 ± 11.33
IL-6 (pg/ml)46.58 ± 8.6795 ± 16.23
TNF-α (pg/ml)56.34 ± 8.33128.98 ± 14.27
TGF-β (pg/ml)16.87 ± 5.3432.45 ± 8.62

IL-17: interleukin- (IL-) 17; IL-1β: interleukin- (IL-) 1β; IL-6: interleukin- (IL-) 6; TNF-α: tumor necrosis factor-α; TGF-β: transforming growth factor-β. Data are expressed as mean ± SD with Student’s t-test analysis. , , against the control values.