Propofol Suppresses Proinflammatory Cytokine Production by Increasing ABCA1 Expression via Mediation by the Long Noncoding RNA LOC286367

Figure 1

Effects of LOC286367 on propofol-induced upregulation of ABCA1 in THP-1 macrophages: (a–c) THP-1 macrophages were treated with or without 50 μM of propofol for 24 h; (d–f) THP-1 macrophages were transfected with LV-Mock or LV-LOC286367; (g) THP-1 macrophages were transfected with LV-Mock or LV-LOC286367 and then incubated with or without 50 μM of propofol for 24 h; (a, d, b, e) expression levels of LOC286367 ABCA1 mRNA were analyzed by qPCR; (c, f, g) ABCA1 protein levels were assessed by Western blot. All the results are expressed as mean ± SD from three independent experiments; each being performed in triplicate. vs the control group.

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