Expansion of a Population of Large Monocytes (Atypical Monocytes) in Peripheral Blood of Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Diseases

Table 1

Study population.

	Healthy	Admission	Remission
Age (yr)	56.23 ± 8.60	74.83 ± 8.92	72.35+ 7.98
Gender (M/F)	8/8 (16)	13/9 (22)	9/8 (17)
FEV1/FVC (%)	80.39 ± 7.50	52.10 ± 12.45
FEV1/pred (%)	90.57 ± 7.01	49.53 ± 11.63
WBC (×10^9/L)	5.48 ± 1.50	9.60 ± 3.58	8.10 ± 2.01
Neutrophil (×10^9/L)	4.51 ± 1.07	7.46 ± 3.27	5.77 ± 2.14
Monocyte (×10^9/L)	0.33 ± 0.10	0.64 ± 0.30	0.59 ± 0.21^∗
Lymphocyte (×10^9/L)	1.97 ± 0.73	1.38 ± 0.95	1.80 ± 0.51
Neutrophil (%)	51.10 ± 6.30	76.46 ± 14.44	68.00 ± 9.94^,▲
Monocyte (%)	5.54 ± 1.01	6.57 ± 3.39	7.61 ± 2.17
Lymphocyte (%)	32.14 ± 5.38	15.92 ± 10.93	21.65 ± 8.19^,▲
CRP (mg/L)	<8.3	39.93 ± 28.89	9.94 ± 7.91^▲▲
IL-6 (pg/mL)	3.76 ± 1.21	14.24 ± 11.07	11.75 ± 9.79
IL-8 (pg/mL)	25.43 ± 4.75	77.12 ± 37.96	70.08 ± 33.44

M: male; F: female; FEV1/pred: forced expiration volume in one second % predicted FEV1; FEV1/FVC: forced expiratory volume in one second/forced vital capacity; CRP: C-reactive protein; WBC: white blood cells. Data are expressed as the mean ± SD. , , and versus healthy. and versus AECOPD.