Research Article
Irisin Exerts Neuroprotective Effects on Cultured Neurons by Regulating Astrocytes
Figure 4
Irisin decreased NFκB activity by preventing the phosphorylation and loss of IκBα in cultured astrocytes exposed to Aβ25–35. (a) Representative picture and statistical result showing irisin decreased the NFκB level in astrocytes exposed to Aβ25–35. (b) Representative picture and statistical result showing irisin decreased the p-IκBα level in astrocytes exposed to Aβ25–35. (c) Representative picture and statistical result showing irisin increased the total IκBα level in astrocytes exposed to Aβ25–35. Data are expressed as means ± SEM, vs control, vs Aβ25–35, .
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