The Associations between Toll-Like Receptor 9 Gene Polymorphisms and Cervical Cancer Susceptibility

Table 4

Meta-analysis results of rs187084 based on five genetic models.

Genetic models	OR (95% CI)	p value	Heterogeneity		Effects model
			I ^2 (%)	p value
Allele model (C versus T)
Overall	1.15 (1.03, 1.29)	0.02	43	0.15	F
Race
Chinese Han	1.06 (0.92, 1.23)	0.39	0	0.38	F
Caucasian	1.33 (1.10, 1.61)	0.004	—	—	—
Dominant model (CC + CT versus TT)
Overall	1.30 (1.11, 1.53)	0.002	0	0.73	F
Race
Chinese Han	1.22 (1.00, 1.50)	0.05	0	0.90	F
Caucasian	1.46 (1.11, 1.92)	0.007	—	—	—
Recessive model (CC versus CT + TT)
Overall	0.94 (0.59, 1.50)	0.79	63	0.04	R
Race
Chinese Han	0.70 (0.34, 1.44)	0.34	52	0.12	R
Caucasian	1.41 (0.98, 2.02)	0.06	—	—	—
Heterozygous genetic model (CT versus TT)
Overall	1.32 (1.11, 1.57)	0.002	0	0.95	F
Race
Chinese Han	1.28 (1.03, 1.59)	0.02	0	0.92	F
Caucasian	1.39 (1.04, 1.86)	0.03	—	—	—
Homozygous genetic model (CC versus TT)
Overall	1.13 (0.71, 1.80)	0.60	56	0.08	R
Race
Chinese Han	0.88 (0.49, 1.59)	0.67	31	0.24	R
Caucasian	1.69 (1.14, 2.51)	0.009	—	—	—

F: fixed-effect model; R: random-effect model; OR: odds ratio; 95% CI: 95% confidence interval.