Increased Expression of TLR10 in B Cell Subsets Correlates with Disease Activity in Rheumatoid Arthritis
TLR10 expression in CD19+ B cell subsets (defined using IgD/CD27) and its association with the DAS28. (a) The percentage of cells expressing TLR10 (%TLR10+) in each subset in the RA subjects and HCs. (b) The percentage of cells expressing TLR10 (%TLR10+) in each group of each subset. (c) The correlation between %TLR10+ expression in each subset and the DAS28. (d) The correlation between the TLR10 MFI in each subset and the DAS28. The data are presented as the median (interquartile range (IQR)) using whisker-box plots, with the boxes representing the IQR and the whiskers representing the min/max values. Differences between individual groups were analysed by the Mann–Whitney test and are described as ( and ); differences among the three groups of RA subjects were analysed by the Kruskal–Wallis test and are described as # ( and ).