Probiotic Mixture Protects Dextran Sulfate Sodium-Induced Colitis by Altering Tight Junction Protein Expressions and Increasing Tregs

Figure 4

The effect of Bifico on the expression and distribution of TJs (a). Microstructural changes in colonic tissues of each group by TEM (80000x magnification) (b) The expressions of JAM-1, occludin, and claudin-4 were detected by Western blot. Group 1 (), group 2 (), group 3 (), group 4 (), and group 5 (). (c) The expressions and distribution of TJs (JAM-1, occludin, and claudin-4) were analyzed by immunohistochemistry (400x magnification). Data are . , , and . Group 1: normal; group 2: Bifico; group 3: colitis; group 4: pretreated-Bifico-colitis; group 5: pretreated + treated-Bifico-colitis.

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