Plasma Asprosin Concentrations Are Increased in Individuals with Glucose Dysregulation and Correlated with Insulin Resistance and First-Phase Insulin Secretion

Table 2

Spearman correlation coefficient of variables associated with circulating asprosin concentration in the study population.

	r	value
Age (year)	−0.010	0.901
Sex (M/F)	−0.014	0.866
BMI (kg/m^2)	0.097	0.249
Wc (cm)	0.185	0.027
WHR	0.002	0.983
SBP (mmHg)	0.089	0.295
DBP (mmHg)	−0.006	0.948
FPG (mmol/L)	0.466	<0.001
2hPG (mmol/L)	0.277	0.003
HbA1c(%/mmol/mol)	0.368	<0.001
TC (mmol/L)	0.017	0.840
TG (mmol/L)	0.282	0.001
HDL-C (mmol/L)	−0.143	0.088
LDL-C (mmol/L)	−0.038	0.652
FINS (mU/L)	0.131	0.120
HOMA-IR	0.29	<0.001
HOMA-β	−0.265	0.001
AUC	−0.478	<0.001
AIR	−0.480	<0.001
GDI	−0.568	<0.001
hsCRP (mg/L)	0.086	0.313

BMI: body mass index; Wc: waist circumference; WHR: waist hip ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; 2hPG; 2 h postchallenge plasma glucose; TC; total cholesterol; TG; triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; FINS: fasting serum insulin; HOMA-IR: homeostasis model assessment for insulin resistance; HOMA-β: homeostasis model assessment for beta-cell function; AUC: area under the curve of the first-phase (0–10 min) insulin secretion; AIR: acute insulin response; GDI: glucose disposition index; hsCRP: hypersensitive C-reactive protein.