TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress

Table 1

Principal characteristics of the subjects.

Demographic and clinical parameters	Value
Number of subjects,	209
Age, years	64 ± 14
Gender (W/M),	163/46
Smoking, (%)	19 (8)
Hypertension, (%)	62 (30)
Diabetes, (%)	18 (9)
Serum parameters
PON1 (U/l)	95 (48–167)
Lp-PLA2 (U/l)	16.4 ± 4.7
Ceruloplasmin (μmol/l)	2.9 (2.2–3.8)
Hydroperoxides (UC)	322 ± 112
AOPP (μmol/l)	70 (57–85)
hs-CRP (nmol/l)	51 (16–121)
TRAIL (pg/ml)	93 ± 36

Data are expressed as % within the group for categorical variables and number of subjects in brackets, mean ± standard deviation for normally distributed continuous variables, and median (interquartile range) for nonnormally distributed continuous variables. PON1: paraoxonase 1; Lp-PLA₂: lipoprotein phospholipase A2; AOPP: advanced oxidation protein products; hs-CRP: high-sensitivity C-reactive protein.