Interleukin-17: Potential Target for Chronic Wounds

Table 1

IL-17 family.

Subtype	Reported biological sources	Heterodimer receptor subunits
A	Mast cells, macrophages, neutrophils, ILC3, ɣδ-T, NKT, CD8^+, TH17 [9]	RA/RC [9]
B	Gastrointestinal tract, pancreas, gonadal tissue, chondrocytes, synovial membrane, neurons, lymphocytes [40, 60]	RA/RB [40]
C	Epithelial cells in the colon, trachea, and skin [32]	RA/RE [32]
D	Pancreas, adipose, skeletal muscle, brain, heart, lung [61]	Unidentified
E	Mast cells, macrophages, eosinophils, basophils, respiratory epithelium, and mucosa [9]	RA/RB [9]
F	Mast cells, macrophages, neutrophils, ILC3, ɣδ-T, NKT, CD8^+, TH17 [9]	RA/RC [9]