Inhibition of MAPK and STAT3-SOCS3 by Sakuranetin Attenuated Chronic Allergic Airway Inflammation in Mice

Table 1

Inflammatory and immune effects of sakuranetin treatment. OVA exposure increased inflammatory cells in blood (cells/mm³), bronchial lavage fluid (BALF 10⁴ cell/mL), IgE, IgG1, IgG2a in serum (OD), and the mass of immune organs (%). ^## and ^# compared with SAL; and compared with OVA; ^€ compared with SK. Data represent from 8 to 11 mice per group.

Data/groups	SAL	OVA	SK	DX
Total cells
Total WBC
Macrophages
Lymphocytes
Neutrophils
Eosinophils		^##
Total WBC		^#	^,##
Macrophages		^#	^$
Lymphocytes		^##
Neutrophils		^##
Eosinophils		^#
OVA-specific antibody (OD)
IgE		^##
IgG1
IgG2a		^##	^##
Organs/mice weight (%)
Thymus		^##
Spleen		^##		^,#,€