Phenolic Compounds Isolated from Calea uniflora Less. Promote Anti-Inflammatory and Antioxidant Effects in Mice Neutrophils (Ex Vivo) and in Mice Pleurisy Model (In Vivo)

Figure 2

Effect of noreugenin (a) and α-hydroxy-butein (b) on cell viability of murine neutrophils. Vehicle = the isolated neutrophils treated only with sterile phosphate-buffered saline (PBS, pH 7.6). LPS = cells treated with LPS (5 μg/mL) only. Noreugenin = cells treated with noreugenin (1-100 μM)+LPS (5 μg/mL). α-Hydroxy-butein = cells treated with α-hydroxy-butein (1-100 μM)+LPS (5 μg/mL). Each group represents the of experiments conducted in triplicate from three to six animals. compared to the control group (Control); ANOVA/Newman–Keuls test.

(a)

(b)