Amphiregulin Regulates Phagocytosis-Induced Cell Death in Monocytes via EGFR and the Bcl-2 Protein Family

Figure 5

Quantification of PICD via detection of hypodiploid nuclei in PBMO and CBMO. Representative histogram of apoptotic sub-G1 subpopulations of treated PBMO (a; full line: E. coli, dotted line: AREG and E. coli, and grey area: EGF and E. coli). Statistical analysis of the Nicoletti assay 24 h p.i. (statistical analysis using nonpaired Student’s -test with Welch correction; ; ). Immunoblots representing the cytochrome c release after indicated treatment of PBMO (c). Statistical analysis of cytochrome c release (d; nonpaired Student’s -test with Welch correction; ; ).

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