Research Article

Adalimumab Accounts for Long-Term Control of Noninfectious Uveitis Also in the Absence of Concomitant DMARD Treatment: A Multicenter Retrospective Study

Table 1

Baseline demographic and clinical characteristics.

Characteristics
n (% out of 106)

Sex
 Men47 (44.34)
 Women59 (55.66)
Median age (IQR) at onset of uveitis, years29.00 (20.50-40.00)
Associated disease
 No (idiopathic uveitis)12 (11.32)
 Yes94 (88.68)
  Behçet syndrome66 (62.26)
  Other (JIA, PsA, AS, VKH, and IBD)28 (26.42)
Median follow-up, months36.02 (16.27-59.17)
Median duration of uveitis at ADA beginning (IQR), years4.00 (1.00-11.00)
Type of uveitis
 Anterior45 (42.45)
 Posterior and/or panuveitis (and/or intermediate)51 (48.11)
 Unilateral42 (39.62)
 Bilateral64 (60.38)
Previous treatment
 None17 (16.04)
 Only synthetic DMARDs59 (55.66)
 Only biologics7 (6.60)
 Synthetic DMARDs and biologics23 (21.70)
Baseline treatment
 None31 (29.25)
 Only synthetic DMARDs53 (50.00)
 Only biologics7 (6.60)
 Synthetic DMARDs and biologics4 (3.77)
 Missing11 (10.38)
Ocular flare
 In the 12 months before ADA treatment76 (71.70)
 At baseline70 (66.04)

ADA: adalimumab; AS: ankylosing spondylitis; DMARDs: disease-modifying antirheumatic drugs; IBD: intestinal bowel disease; JIA: juvenile idiopathic arthritis; PsA: psoriatic arthritis; VKH: Vogt-Koyanagi-Harada.