circRNA CDR1as Regulated the Proliferation of Human Periodontal Ligament Stem Cells under a Lipopolysaccharide-Induced Inflammatory Condition

Figure 4

circRNA CDR1as mediated LPS-induced inhibition of PDLSC proliferation. (a) A standard curve of cell proliferation and mathematical formula describing OD value and cell number. Cell proliferation of PDLSCs was assessed by CCK-8 assay as indicated with cell numbers in reference to this standard curve obtained under the same conditions in all subsequent experiments. (b) Cell number of LPS-treated PDLSCs was less than that of untreated cells at each examined day, . (c) The efficiency of knockdown of CDR1as in PDLSCs was determined by RT-qPCR. vs. si-NC. (d) The effects of knockdown of CDR1as on the proliferation of PDLSCs. vs. control. (e) The efficiency of overexpression of CDR1as in PDLSCs was determined by RT-qPCR. vs. over-NC. (f) The effects of overexpression of CDR1as on the proliferation of PDLSCs, vs. control.

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