Infection with Opportunistic Bacteria Triggers Severe Pulmonary Inflammation in Lupus-Prone Mice

<div>Tremendous neutrophils were recruited to the lupus lung after infection. B6 and B6/lpr mice were infected with Hi (B6 Hi and B6/lpr Hi). Uninfected mice were set as controls (B6 UI and B6/lpr UI). Two days after infection, all the mice were sacrificed and BALF cells were isolated for analyses. (a) Absolute numbers of BALF cells. (b, c) Alveolar macrophages (CD11b<sup>-</sup>CD11c<sup>+</sup>) and (d, e) neutrophils (CD11b<sup>+</sup>Gr-1<sup>+</sup>) were determined by surface staining. 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This experiment is representative of three individual experiments.</div>

Mediators of Inflammation

fig4

Figure 4

Figure 4: Infection with Opportunistic Bacteria Triggers Severe Pulmonary Inflammation in Lupus-Prone Mice 