Research Article
Role of SOCS2 in the Regulation of Immune Response and Development of the Experimental Autoimmune Encephalomyelitis
Figure 5
Role of SOCS2 in the hematopoietic and nonhematopoietic compartments in EAE development. EAE was induced in chimeric SOCS2-/-donor→WT EAEhost, WTdonor→SOCS2-/- EAEhost, WTdonor→WT EAEhost, and SOCS2-/-donor→SOCS2-/- EAEhost. (a) Score was monitored by clinical signs comparing WT with SOCS2-/- mice. (b) Weight loss percentage and (c) survival were also assessed daily comparing WT with SOCS2-/- animals. Data represent the (statistical significance was performed by one-way ANOVA, with Tukey posttest and survival log rank test).
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